Non-uniform aspects of the SARS-CoV-2 intraspecies evolution reopen question of its originArticle Published on 2022-12-012022-11-16 Journal: International journal of biological macromolecules [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome beta-coronavirus Characteristics conducted conserved coronavirus disease Coronavirus-2 COVID-19 distribution Evenly-uneven Evidence Evolution Frequency functional furin cleavage Furin cleavage site (FCS) hypothese Hypothesis Invariant regions Mutation mutations pandemic Pandemics Protein question Region residue residues SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2. Support the SARS-CoV-2 Transmissibility unique variants virulence virus [DOI] 10.1016/j.ijbiomac.2022.09.184 PMC 바로가기
SARS-CoV-2 vaccine breakthrough reinfection in a health-care worker of Iraq: A case report이라크 의료 종사자에서 SARS-CoV-2 백신 획기적인 재감염: 사례 보고Case Reports Published on 2022-11-302022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 변종, [키워드] affected Breakthrough infection Case report circulating variants completion COVID-19 COVID-19 pandemic delta variant Effectiveness globe Health health worker health-care Infection Intervention Iraq Isolation many case many cases mediated immunity Patient question raised Reinfection reported Respiratory illness RT-PCR SARS-CoV-2 SARS-CoV-2 vaccine scarcity severe respiratory illness symptom severity the SARS-CoV-2 vaccinated individuals vaccination Vaccine vaccine breakthrough infection vaccine breakthrough infections vaccine-mediated immunity variants variants. Wuhan Wuhan, China [DOI] 10.1080/21645515.2022.2055947 PMC 바로가기 [Article Type] Case Reports
Recent advances in applying G-quadruplex for SARS-CoV-2 targeting and diagnosis: A reviewArticle Published on 2022-11-302022-11-15 Journal: International journal of biological macromolecules [Category] SARS, 변종, 치료기술, 치료제, [키워드] accumulating addressed antiviral drug Care caused coronavirus SARS-CoV-2 diagnostic functions G-quadruplex Health Host Immune escape Intervention Ligand ligands neutralizing antibody nucleic acid pandemic polymerases protease Protein question recent regulate SARS-CoV-2 SARS-CoV-2 detection Structure targeting Targeting. Treatment strategies Vaccine variant virus virus [DOI] 10.1016/j.ijbiomac.2022.09.152 PMC 바로가기
Multiple genome analytics framework: The case of all SARS-CoV-2 complete variantsArticle Published on 2022-11-202022-11-16 Journal: Journal of biotechnology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] accelerated Algorithm Algorithms analyses analytics ARPaD bioinformatics Biotechnology can be used center Comparisons Complete computational tool COVID-19 dataset Efficiency framework Genome genome sequence genomic help information introduced knowledge LERP-RSA meta-analyses MPaD MuGA Multiple Multiple genome analytics framework organism palindrome pattern polymerase chain primer problem problems question repeated required resource resources SARS-CoV-2 SARS-CoV-2 genome sequence sequence SPaD. Structure text mining Topic variant variants [DOI] 10.1016/j.jbiotec.2022.09.015 PMC 바로가기
SARS-CoV-2 quasi-species analysis from patients with persistent nasopharyngeal sheddingArticle Published on 2022-11-042022-11-16 Journal: Scientific Reports [Category] SARS, 변종, [키워드] Analysis asked both groups clade Consequences Control COVID 19 deviation Evolution of SARS-CoV-2 genomic greater Human immune system immune evasion increase Infectious virus Interaction intra-individual investigated Mutation N501Y nasopharyngeal no significant difference P681H pandemic Patient patients performed persistence Prevent question RNA virus SARS-CoV-2 Sequencing Standard survival the SARS-CoV-2 therapeutic two group Variability variants viral propagation viral variant [DOI] 10.1038/s41598-022-22060-z PMC 바로가기
Anxiety and depression in the post-pandemic era: concerns about viral mutation and re-outbreakArticle Published on 2022-11-032022-11-16 Journal: BMC Psychiatry [Category] SARS, 변종, [키워드] Anxiety changes in China city clinically Complete conducted convenience sampling coronavirus COVID-19 critically ill patients Depression depression. difference East effective Factor female GAD-7 groups Health healthy help illness IMPROVE infected patient infected patients likelihood logistic regression model males mental health no significant difference outbreak pandemic Patient Perception PHQ-9 Population Psychological psychological reaction public health system question questionnaire Questionnaires reduced reported required risk factor severity significant level Support the patient variant viral mutation [DOI] 10.1186/s12888-022-04307-1 PMC 바로가기
Novel hit of DPP-4Is as promising antihyperglycemic agents with dual antioxidant/anti-inflammatory effects for type 2 diabetes with/without COVID-19Research article Published on 2022-11-012022-10-05 Journal: Bioorganic chemistry [Category] SARS, 신약개발, [키워드] activities activity addition Anti-inflammatory antioxidant Cell Co-receptor consequence COVID-19 CRP derivatives DPPH Effect evaluated IL-6 infections molecular docking not correlated novel OGT Patient Pyrimidinones question raised SARS-CoV-2 screened small molecule drug tested therapy Treatment type 2 diabete type 2 diabetes [DOI] 10.1016/j.bioorg.2022.106092 [Article Type] Research article
Discovery of a tRNA-like base sequence in the coronavirus genome and possible mechanism of actionArticle Published on 2022-11-012022-11-16 Journal: Genes & genomics [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome base Base sequence Cloverleaf model of tRNA complementary coronavirus Evidence function genetic component Genome homology human gene intron involved mechanism of action Messenger RNA molecular Mutation mutation. produced question robust SARS-CoV SARS-CoV-2 sequence therapeutic agents viruses [DOI] 10.1007/s13258-022-01299-w PMC 바로가기
Prevalence, trajectory over time, and risk factor of post-COVID-19 fatigueArticle Published on 2022-11-012022-11-15 Journal: Journal of psychiatric research [Category] 치료제, [키워드] bootstrap Characteristics Clarifying collected Course COVID-19 COVID-19 severity Depression depressive evaluated fatigue identify independent Intervention mechanism overlapping Patient physical post-COVID fatigue post-COVID syndrome predict predicted predictor Prevalence question rehabilitation remained reported symptom risk factor SARS-CoV-2 SARS-CoV-2. scale severity specific treatment Symptom Symptoms syndrome trajectory worsening [DOI] 10.1016/j.jpsychires.2022.08.008 PMC 바로가기
Structural basis for mouse receptor recognition by SARS-CoV-2 omicron variantArticle Published on 2022-11-012022-11-16 Journal: Proceedings of the National Academy of Sciences of [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 acute respiratory syndrome Angiotensin-converting enzyme coronavirus COVID-19 domain Effect ENhance human ACE2 human Angiotensin-converting enzyme humans infect investigated mouse angiotensin-converting enzyme 2 Mutation Mutational hotspots N501Y Omicron variant question raised RBD receptor Receptor-binding domain (RBD). SARS-CoV-2 Spread the RBD viral adaptation X-ray X-ray crystallography [DOI] 10.1073/pnas.2206509119 PMC 바로가기